Endocrine Abstracts

Adrenocortical carcinoma is a rare heterogeneous neoplasm with a poor prognosis. Most patients present with symptoms related to steroid hormone excess or presence of an abdominal mass, while less frequently they are diagnosed incidentally during clinical exploration for other causes. In children, adrenocortical tumors are most commonly found associated with mutations of the TP53 tumor suppressor gene and have the highest incidence in southern Brazil. Several clinical and patho...